Yoro and Sancho start for United
Despite the youthful look of his 26-man squad, Erik ten Hag names as an experienced side as possible to take on Rangers.
Most notably is a first Manchester United appearance for 18-year-old Leny Yoro following his £52m move from Lille two days ago.
Also starting is the previously exiled Jadon Sancho, back at the club after a season on loan at Borussia Dortmund.
Also included are Andre Onana – back in goal despite the heroics of Radek Vitek against Rosenborg – as well as Jonny Evans, Mason Mount and captain Casemiro.
Eighteen-year-old Ethan Wheatley leads the line for the Red Devils.
Man Utd (4-2-3-1): Onana; Wan-Bissaka, Yoro, Evans, Murray; Casemiro, Collyer; Amad, Mount, Sancho; Wheatley.
Subs: Mee, Vitek, Aljofree, Amass, Bennett, Fish, Jackson, Ogunneye, Oyedele, J. Fletcher, Hannibal, Mather, Scanlon, Ennis, Hugill